Nitrosigine® delivers a bioavailable form of arginine shown to rapidly boost the body’s nitric oxide production.
Superior nitric oxide booster
Helps fuel physical performance by supporting oxygen and nutrient delivery to working muscles
Promotes healthy blood flow
Nitric oxide production supports cardiovascular function, men’s sexual health, and vigor and vitality
About Nitrosigine
Nitrosigine is a patented complex of Bonded Arginine Silicate. By promoting the body’s nitric oxide production, Nitrosigine supports healthy aging across key areas of well-being including physical performance, sexual vitality, cognition, and cardiovascular health.
What Makes Nitrosigine Unique
- Fast acting—boosts nitric oxide production within 2 hours
- Provides a unique, bioavailable form of arginine
- More potent gram for gram compared to other leading nitric oxide-promoting ingredients
How it Works
Nitrosigine boosts nitric oxide within the body, delivering the power of this miracle molecule in support of overall wellness. Nitric oxide is key to vitality, responsible for promoting optimal blood flow, as well as for supporting vascular health, neuronal function, and even sexual health.
Nitrosigine is rapidly absorbed within 30 minutes of consumption and quickly goes to work, boosting nitric oxide production within just 2 hours. With just a 1.5g dose, Nitrosigine increases blood flow by boosting nitric oxide levels at ⅕ the dose of citrulline, making it more potent gram for gram.
white paper
Research-Powered Insights
Access resources that demonstrate the science, benefits, and applications of Nitrosigine.
Superior Nitric Oxide Booster
- Nitrosigine delivers a unique and bioavailable form of arginine in the body
- Rapidly boosts production of nitric oxide within 2 hours
- Nitric oxide is a miracle molecule critical to maintaining the vitality of physiological systems
Fuels Physical Performance
- Nitrosigine promotes better blood flow helping to feed and fuel working muscles
- Supports the delivery of the nutrients and oxygen muscles need to perform at their peak
Boosting Blood Flow
- Nitrosigine quickly increases vasodilation to promote healthy, smooth blood flow
- Nitric oxide supports the health of the cells so they remain flexible and responsive
- Healthy blood flow can help support men’s sexual function
Supporting Vigor and Vitality
- Nitrosigine is shown to enhance mental flexibility and cognitive function as well as improve feelings of energy
- Maintaining nitric oxide levels supports healthy blood flow to and within the brain
Science That
Powers Nitrosigine




Application Opportunities
Capsules
RTD Beverages
Powders
Tablets
Bars & Snacks
Gummies & Gels
Capsules
RTD Beverages
Powders
Tablets
Bars & Snacks
Gummies & Gels
Discover the Nitrosigine Difference
video
Nitrosigine in Action
Nitric oxide is a key molecule supporting overall well-being and healthy aging. Discover how nitric oxide-boosting ingredients, like Nitrosigine, can support an active lifestyle, cardiovascular health, cognitive health, and more.
Where to Find Nitrosigine
Everwell Health powers leading consumer brands with exclusive ingredient solutions.
Discover our ingredients in action on product labels across the marketplace.
Zallevo Mind Sync
Zallevo Mind Sync
Zallevo Mind Sync
The Latest

Functional Beverages
This insightful application guide explores key consumer drivers and provides science-backed solutions to overcome technical hurdles in RTD development.

The Future of Aging Well
Using proprietary research gathered in an exclusive two-part study, we offer insights into healthy aging today.

Say Yes to the power of NO: The Science Behind Nitric Oxide and Nitrosigine
Nitric oxide (NO) is a crucial molecule in the human body, playing a vital role in various physiological processes. It acts as a signaling molecule, helping to regulate blood flow, oxygen delivery, and support working muscles. NO is particularly important for cardiovascular health, as it aids in the dilation of blood vessels, maintaining blood pressure and promoting circulation.